Ms. Edi Kachal

University of Szeged, Hungary

Abstract Title: Synthesis and Characterization of Various Silver Nanoparticles Encapsulated in Silica Shell .

Biography:

Edi Kachal is a PhD student in the Doctoral School of Chemistry at University of Szeged. Hungary, where she is specializing in the development of silver-based nanoparticles and their potential biomedical applications. Her research explores the environmentally friendly methods of synthesizing AgNPs using plant extracts. Silver core-silica shell nanostructures, with an emphasis on enhancing their biocompatibility and targeting efficiency for cancer treatment specially has been center of her research interest. She has presented her findings in an international conference including 29th International Symposium on Analytical and Environmental Problems. Szegedi Tudományegyetem, Szeged. Edi completed her B.Sc. in Chemistry Science at the University of Duhok where she graduated with honors and MSc in Biomedical Science at the university of Chester, England UK. At this conference, she is excited to share her latest findings research work on the potential of Ag NPs and specially, silver core-silica shell (Ag@Sio2) nanostructure processing and their role in advancing precision medicine and engage with experts in the field.

Research Interest:

The silver core-silica shell nanoparticles synthesis and characterization are reported as a promising approach in biomedical filed such as targeted cancer therapy and imaging applications. While colloidal silver nanoparticles (AgNPs) hold promises their usage is limited by biocompatibility issues, toxicity, stability, and environmental concerns, to overcome these challenges, increase biocompatibility for biomedical applications, or even modify the optical properties of AgNps, the idea of creating a core-shell structure has been introduced. Based on this knowledge in this study, spherical shape various silver nanoparticles with an average diameter of 5–28 nm were synthesized via a chemical reduction and green reagents (tea and coffee extract), followed by the encapsulation of these AgNPs within a silica shell using the Stöber method widely-used sol-gel route. The silica shell was formed by hydrolysis-condensation polymerization of tetraethylorthosilicate (TEOS) on the surface of the Ag particles with average size 50 to 60 nm. The resulting Ag@SiO2 nanocomposites were characterized using various techniques, including transmission electron microscopy (TEM), dynamic light scattering (DLS), and UV-Vis spectroscopy, confirming the uniform size and morphology of the nanoparticles, as well as their optical properties and Fouriertransform infrared spectroscopy (FTIR) for structural stability of the silica shell was assessed.